PT-141 (Bremelanotide)

A synthetic melanocortin analog researched for its selective interaction with MC3R and MC4R receptors. It is a common laboratory tool for examining G-protein–coupled receptor (GPCR) activation and central neuroendocrine signaling pathways. For research use only. Not for human consumption.

Description

PT-141 is a synthetic research peptide developed from structural modifications of the melanocortin analog Melanotan II. In experimental models, PT-141 has been studied for its selective interaction with melanocortin receptors, particularly MC3R and MC4R, which are involved in central neuropeptide signaling pathways. 

Preclinical research commonly utilizes PT-141 to examine G-protein–coupled receptor (GPCR) activation, hypothalamic signaling mechanisms, and downstream neuroendocrine modulation. Its receptor selectivity and defined mechanism of action make PT-141 a useful tool for investigating melanocortin system biology and neuronal signaling dynamics in controlled laboratory environments. 

For research use only. Not for human consumption. 

 

References 

Wessells H, et al. Journal of Urology. 2003;170(2 Pt 1):627–632.
Shadiack AM, et al. Journal of Sexual Medicine. 2007;4(1):95–104.
Hadley ME. Annals of the New York Academy of Sciences. 2006;994:419–430. 

 

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