A ubiquitous coenzyme utilized in research to study metabolic and redox biology. It serves as an essential substrate for sirtuins and PARPs, playing a critical role in DNA repair, mitochondrial oxidative pathways, and cellular stress adaptation. For research use only. Not for human consumption.
NAD⁺ (nicotinamide adenine dinucleotide) is a ubiquitous cellular coenzyme studied for its central role in metabolic and redox biology. In experimental systems, NAD⁺ participates in electron transfer reactions by interconverting between its oxidized (NAD⁺) and reduced (NADH) forms, supporting key processes involved in cellular energy metabolism, including glycolysis and mitochondrial oxidative pathways.
In addition to its role in energy regulation, NAD⁺ functions as an essential substrate for several enzyme families, including sirtuins and poly(ADP-ribose) polymerases (PARPs). These enzymes are involved in mechanisms related to DNA repair, transcriptional regulation, and cellular stress adaptation. As a result, NAD⁺ is frequently utilized in preclinical research exploring mitochondrial function, metabolic regulation, cellular resilience, and molecular pathways associated with aging and stress response biology.
For research use only. Not for human consumption.
References
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Yoshino J, et al. Cell Metabolism. 2018;27(3):529–547.